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Commissioned Research: Ongoing Projects


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All ongoing research projects funded by the NHS National R & D Programme on Asthma Management are listed below, by priority area. For more detailed information about an individual project please click on the respective title.

PRIORITY 1: Delineation of predictors of response to the treatment of wheezing illness in children

A randomised controlled trial of oral prednisolone for viral-wheeze in preschool children with stratification for serum level of eosinophil protein X
Dr Jonathan Grigg, University of Leicester
Start date: 01/03/99 Planned end date: 28/02/02 Estimated cost: £197,598

Effect of inhaled corticosteroids on airway resistance measured by the interrupter technique (R int)in preschool children with wheeze and cough)
Dr Sheila McKenzie, Royal London Hospitals NHS Trust, London
Start date: 18/01/99 Planned end date: 17/01/01 Estimated cost:£105,745

Identification of indicators of poor prognosis in a longitudinal birth cohort study of children at increased risk of developing asthma
Dr Jeremy Cogswell, Poole Hospital NHS Trust
Start date: 01/04/99 Planned end date: 31/03/00 Estimated cost: £39,299

Predictors of prognosis of wheezing in infancy and early childhood in the ALSPAC cohort
Professor David Strachan, St George's Hospital Medical School
Start date: 01/01/99 Planned end date: 31/12/00Estimated cost: £147,694

The natural history of infant wheezing: clinical outcome at age six and its prediction
Dr Joanne Clough, University of Southampton
Start date: 01/04/99 Planned end date: 30/06/00 Estimated cost: £109,882


PRIORITY 2: Evaluation of interventions based on individual patients or households to prevent the development of asthma, reduce its severity or improve its prognosis

Dietary magnesium or vitamin C supplementation as an adjunct to usual asthma therapy: a community-based investigation
Professor John Britton, University of Nottingham
Start date: 20/05/98 Planned end date: 19/09/00 Estimated cost:  £270,622

The effect of mite allergen avoidance by the use of allergen impermeable bedding, on asthma control in adults
Professor Ashley Woodcock, North West Lung Centre, Univeristy of Manchester
Start date: 01/05/98 Planned end date: 30/04/01 Estimated cost: £728,678


PRIORITY 3: Evaluating and synthesising outcome measures for asthma in adults and children

A systematic review of the outcomes used to assess therapy for asthma
Professor Paul Jones, St. George's Hospital Medical School
Start date: 01/06/98Planned end date: 01/12/00Estimated cost: £99,584


PRIORITY 4: Review of gaps in evidence for current guidelines on asthma management, followed by primary research to address these

Systematic reviews of inhaled steroid therapy in asthma
Professor Paul Jones, St. George's Hospital Medical School
Start date: 01/06/98Planned end date: 01/06/00Estimated cost: £82,979

Can severe exacerbations of asthma be predicted and prevented?
Dr Timothy Harrison, University of Nottingham
Start date: 01/12/98Planned end date: 28/02/01Estimated cost: £180,653


PRIORITY 5: Evaluation of risks, benefits and cost of long term treatment for asthma

Risk factors for asthma deaths: A national case control study
Professor Ross Anderson, St. George's Hospital Medical School
Start date: 01/01/98Planned end date: 01/09/00Estimated cost: £228,210

Clinical and economic implications of stepping down inhaled corticosteroids in patients with chronic stable asthma
Professor Neil Thomson, University of Glasgow
Start date: 01/01/99Planned end date: 31/12/01Estimated cost: £401,646


PRIORITY 6: Social and psychological influences on the use of asthma services leading to the development and evaluation of strategies to address these problems

A controlled study evaluating relative benefits of two types of review after an A&E attendance
Dr Leisl Osman, University of Aberdeen
Start date: 01/10/97Planned end date: 01/03/01Estimated cost: £99,762

Clinical and cost-effectiveness of a cognitive behavioural intervention for improved self management in adults with psychological complications of asthma
Professor Glenys Parry, University of Sheffield
Start date: 29/09/97     Planned end date: 07/03/01Estimated cost: £124,189


PRIORITY 7: Identification and management of patients at risk from severe attacks of asthma

The derivation and validation of an asthma severity score for use in general practice
Dr David Halpin, University of Exeter
Start date: 01/10/97Planned end date: 31/03/00Estimated cost: £75,479

Enhancing self-regulation skills in teenagers with severe asthma through a nurse-led intervention: a randomised controlled trial
Ms Philippa Madge, Yorkhill NHS Trust Glasgow
Start date: 01/10/99Planned end date: 30/09/02 Estimated cost: £115,544


PRIORITY 8: Evaluation of methods of communication between health professionals and patients, teachers and carers

A controlled evaluation of benefits of discharge planning after hospitalisation for acute asthma
Dr James Friend, University of Aberdeen
Start date: 01/03/98Planned end date: 28/02/01Estimated cost: £107,791

Evaluation by case study of a school-based intervention to improve the management and decrease the morbidity of asthmatic children
Professor John Warner, University of Southampton
Start date: 01/09/98Planned end date: 01/09/01Estimated cost: £247,547 

A randomised controlled trial (RCT) to evaluate the acceptability and cost-implications of using multimedia to educate patients with asthma on inhaler administration
Dr Larry Goodyer, King’s College London
Start date: 01/10/98Planned end date: 01/04/00Estimated cost: £57,601


PRIORITY 9: Evaluation of models of delivery of care for asthma management in different settings

Cost-effectiveness of asthma management with and without a specialist outreach service
Dr Patrick White, King's College School of Medicine and Dentistry
Start date: 01/09/97Planned end date: 31/08/98Estimated cost: £23,946

Focusing on those in need: A symptom-based outcome questionnaire for postal invitation and audit in a primary care asthma clinic
Dr Charlotte Paterson, Warwick House Medical Centre
Start date: 01/02/98Planned end date: 31/11/99Estimated cost: £10,334

Improving asthma care for teenagers via secondary school clinics
Dr Christopher Salisbury, University of Bristol
Start date: 11/01/99Planned end date: 10/01/01Estimated cost: £127,312


PRIORITY 10: Investigation of beliefs of patients with asthma

An epidemiological investigation of asthma care in older people
Dr Lindsey Dow, University of Bristol
Start date: 01/10/98 Planned end date: 31/07/2000Estimated cost: £136,573

Managing asthma: Attitudes to asthma and asthma therapy among South Asian cultural groups
Ms Helen Lomax, Institute for Health Services Research, University of Luton
Start date: 01/03/98Planned end date: 30/04/99Estimated cost: £51,951

Health beliefs, behaviour and goals of professional health carers and adolescents with asthma: exploring and matching perspectives for improving concordance with self-management
Alexandra Greene, University of St Andrews
Start date: 01/10/99Planned end date: 30/09/01Estimated cost: £107,849

A qualitative investigation of treatment goals at different levels of asthma severity
Professor Frank Sullivan, University of Dundee
Start date: 22/02/99Planned end date: 21/09/01Estimated cost: £83,152

An analysis of the way in which patients make judgements concerning their self-management of asthma
Professor Paul Jones, St. George's Hospital Medical School
Start date: 01/05/99Planned end date: 31/10/01 Estimated cost: £105,408

An exploration of patient, parent and professional knowledge, beliefs and behaviour regarding the contribution of allergen avoidance in the management of asthma
Professor John Warner, University of Southampton
Start date: 01/10/99 Planned end date: 30/09/01 Estimated cost: £131,693

A descriptive study of decisional role preference and priority information needs in adult asthma patients
Professor Karen Luker, University of Manchester
Start date: 01/04/99 Planned end date: 30/09/01 Estimated cost: £153,428


Commissioned Projects index page


All contents copyright © 1999, NHS Executive. All rights reserved.
Page maintained by Philip Green
Last updated 09 November 1999
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